Abstract
Neutropenic fever is a common and potentially life-threatening condition in patients treated for cancer. Rapid initiation of appropriate antimicrobial therapy is necessary to decrease the risk of mortality. Most infections are due to gram-positive organisms, but themortality rate is higher for gram-negative infections. Multidrugresistant organisms are an emerging threat to neutropenic patients. Increasing data suggest that the pathophysiology of neutropenic fever and neutropenic sepsis is substantially different from non-neutropenic fever and sepsis. Additional research is needed to both further elucidate the pathogenesis of neutropenic fever and to develop additional effective antimicrobials.
Original language | English (US) |
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Title of host publication | Oncologic Critical Care |
Publisher | Springer International Publishing |
Pages | 1297-1311 |
Number of pages | 15 |
ISBN (Electronic) | 9783319745886 |
ISBN (Print) | 9783319745879 |
DOIs | |
State | Published - Oct 12 2019 |
Keywords
- Fever
- Fungal
- Gram negative
- Gram positive
- Neutropenia
- Neutropenic
- Sepsis
ASJC Scopus subject areas
- General Medicine