Neurotransmitter transporters (plus): a promising new gene family

George R. Uhl

Research output: Contribution to journalArticlepeer-review

155 Scopus citations

Abstract

Neurotransmitter transporter genes encode proteins with 12 putative transmembrane regions, which mediate Na+ -dependent reaccumulation of released neurotransmitters into presynaptic terminals and are the sites of action of important abused and therapeutic drugs. Studies of these genes show promise for improving our understanding of transport mechanisms and modes of drug action, and may even uncover previously unanticipated neurotransmitters.

Original languageEnglish (US)
Pages (from-to)265-268
Number of pages4
JournalTrends in Neurosciences
Volume15
Issue number7
DOIs
StatePublished - 1992

ASJC Scopus subject areas

  • General Neuroscience

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