Abstract
Sarcoidosis is an idiopathic multisystem granulomatous disorder. Neurologic manifestations in sarcoidosis are varied and making a diagnosis of neurosarcoidosis can be difficult as it mimics various other neurologic diseases. Knowledge of the syndromes associated with neurosarcoidosis can help guide the diagnostic evaluation. Definitive diagnosis requires neurologic tissue evidence of noncaseating granuloma, but in practice probable diagnosis is often made through nonneurologic biopsy and a characteristic syndrome and imaging. Treatment remains empiric, but new advances in immunologic therapy hold promise for effective and less-toxic regimens.
Original language | English (US) |
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Pages (from-to) | 386-394 |
Number of pages | 9 |
Journal | Seminars in neurology |
Volume | 34 |
Issue number | 4 |
DOIs | |
State | Published - Sep 1 2014 |
Externally published | Yes |
Keywords
- aseptic meningitis
- cranial neuropathy
- granuloma
- myelitis
- neurologic complications
- neurosarcoidosis
- sarcoidosis
ASJC Scopus subject areas
- Neurology
- Clinical Neurology