Neurosarcoidosis

Shruti P. Agnihotri, Tarun Singhal, Barney J. Stern, Tracey A. Cho

Research output: Contribution to journalArticlepeer-review

Abstract

Sarcoidosis is an idiopathic multisystem granulomatous disorder. Neurologic manifestations in sarcoidosis are varied and making a diagnosis of neurosarcoidosis can be difficult as it mimics various other neurologic diseases. Knowledge of the syndromes associated with neurosarcoidosis can help guide the diagnostic evaluation. Definitive diagnosis requires neurologic tissue evidence of noncaseating granuloma, but in practice probable diagnosis is often made through nonneurologic biopsy and a characteristic syndrome and imaging. Treatment remains empiric, but new advances in immunologic therapy hold promise for effective and less-toxic regimens.

Original languageEnglish (US)
Pages (from-to)386-394
Number of pages9
JournalSeminars in neurology
Volume34
Issue number4
DOIs
StatePublished - Sep 1 2014
Externally publishedYes

Keywords

  • aseptic meningitis
  • cranial neuropathy
  • granuloma
  • myelitis
  • neurologic complications
  • neurosarcoidosis
  • sarcoidosis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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