Neuropsychological evaluation for detecting alterations in the central nervous system after chemical exposure

Research output: Contribution to journalArticlepeer-review

Abstract

Individuals with multiple chemical sensitivity (MCS) report decreased attention/concentration, memory loss, disorientation, confusion, fatigue, depression, irritability, decreased libido, sleep disturbances, headaches, and weakness. These neurobehavioral symptoms represent possible alterations in the central nervous system (CNS). The evaluation of neurobehavioral functioning using neuropsychological techniques provides an indirect method for determining the integrity of the CNS. However, caution must be used in interpreting neuropsychological test results, since this technique is extremely sensitive but is not specific. Clinically significant aberrant test performance may be noted after chemical exposure as well as with other diseases of the CNS. In addition, neuropsychiatrie conditions such as anxiety and depression are often manifested as cognitive difficulties that are similar in pattern to the cognitive dysfunction caused by toxic chemicals. Herein, limitations and cautions in the interpretations of neuropsychological test results are discussed.

Original languageEnglish (US)
Pages (from-to)s48-s51
JournalRegulatory Toxicology and Pharmacology
Volume24
Issue number1 II
DOIs
StatePublished - 1996

ASJC Scopus subject areas

  • Toxicology

Fingerprint Dive into the research topics of 'Neuropsychological evaluation for detecting alterations in the central nervous system after chemical exposure'. Together they form a unique fingerprint.

Cite this