Abstract
We sought to elucidate the existence of neuropsychological subtypes in Complex Regional Pain Syndrome (CRPS). One hundred thirty seven patients with CRPS were administered tests that assess executive control, naming/lexical retrieval, and declarative memory. A 2-step cluster analysis that does not require any a priori specification regarding the number of clusters, classified patients into three groups. Group 1 obtained scores that were in the average range on all tests (n = 48; normal CRSP group). Group 2 (n = 58; dysexecutive CRSP group) presented with mild impairment or statistically low average test performance on working memory/verbal fluency tests. Group 3 (n = 31; global CRSP group) produced scores in the statistically low average/borderline range on all tests with particularly reduced scores on naming/declarative memory tests. Between-group analyses found that the CRPS group 1 obtained higher scores than CRPS groups 2 and 3 on all tests. However, groups 2 and 3 were equally impaired on executive tests. CRPS group 3 was impaired on tests of naming/memory tests compared to the other groups. Significant neuropsychological deficits are present in 65% of patients, with many patients presenting with elements of a dysexecutive syndrome and some patients presenting with global cognitive impairment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 566-573 |
| Number of pages | 8 |
| Journal | Journal of the International Neuropsychological Society |
| Volume | 16 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 2010 |
| Externally published | Yes |
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Keywords
- Complex Regional Pain Syndrome
- Declarative memory
- Executive functioning
- Neuropathic pain
- Neuropsychological functioning
- Reflex Sympathetic Dystrophy
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health
- Clinical Psychology
- Neuroscience(all)
Cite this
Neuropsychological deficits associated with Complex Regional Pain Syndrome. / Libon, David J.; Schwartzman, Robert J.; Eppig, Joel; Wambach, Denene; Brahin, Eric; Lee Peterlin, B.; Alexander, Guillermo; Kalanuria, Atul.
In: Journal of the International Neuropsychological Society, Vol. 16, No. 3, 05.2010, p. 566-573.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neuropsychological deficits associated with Complex Regional Pain Syndrome
AU - Libon, David J.
AU - Schwartzman, Robert J.
AU - Eppig, Joel
AU - Wambach, Denene
AU - Brahin, Eric
AU - Lee Peterlin, B.
AU - Alexander, Guillermo
AU - Kalanuria, Atul
PY - 2010/5
Y1 - 2010/5
N2 - We sought to elucidate the existence of neuropsychological subtypes in Complex Regional Pain Syndrome (CRPS). One hundred thirty seven patients with CRPS were administered tests that assess executive control, naming/lexical retrieval, and declarative memory. A 2-step cluster analysis that does not require any a priori specification regarding the number of clusters, classified patients into three groups. Group 1 obtained scores that were in the average range on all tests (n = 48; normal CRSP group). Group 2 (n = 58; dysexecutive CRSP group) presented with mild impairment or statistically low average test performance on working memory/verbal fluency tests. Group 3 (n = 31; global CRSP group) produced scores in the statistically low average/borderline range on all tests with particularly reduced scores on naming/declarative memory tests. Between-group analyses found that the CRPS group 1 obtained higher scores than CRPS groups 2 and 3 on all tests. However, groups 2 and 3 were equally impaired on executive tests. CRPS group 3 was impaired on tests of naming/memory tests compared to the other groups. Significant neuropsychological deficits are present in 65% of patients, with many patients presenting with elements of a dysexecutive syndrome and some patients presenting with global cognitive impairment.
AB - We sought to elucidate the existence of neuropsychological subtypes in Complex Regional Pain Syndrome (CRPS). One hundred thirty seven patients with CRPS were administered tests that assess executive control, naming/lexical retrieval, and declarative memory. A 2-step cluster analysis that does not require any a priori specification regarding the number of clusters, classified patients into three groups. Group 1 obtained scores that were in the average range on all tests (n = 48; normal CRSP group). Group 2 (n = 58; dysexecutive CRSP group) presented with mild impairment or statistically low average test performance on working memory/verbal fluency tests. Group 3 (n = 31; global CRSP group) produced scores in the statistically low average/borderline range on all tests with particularly reduced scores on naming/declarative memory tests. Between-group analyses found that the CRPS group 1 obtained higher scores than CRPS groups 2 and 3 on all tests. However, groups 2 and 3 were equally impaired on executive tests. CRPS group 3 was impaired on tests of naming/memory tests compared to the other groups. Significant neuropsychological deficits are present in 65% of patients, with many patients presenting with elements of a dysexecutive syndrome and some patients presenting with global cognitive impairment.
KW - Complex Regional Pain Syndrome
KW - Declarative memory
KW - Executive functioning
KW - Neuropathic pain
KW - Neuropsychological functioning
KW - Reflex Sympathetic Dystrophy
UR - http://www.scopus.com/inward/record.url?scp=77952548758&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952548758&partnerID=8YFLogxK
U2 - 10.1017/S1355617710000214
DO - 10.1017/S1355617710000214
M3 - Article
C2 - 20298641
AN - SCOPUS:77952548758
VL - 16
SP - 566
EP - 573
JO - Journal of the International Neuropsychological Society
JF - Journal of the International Neuropsychological Society
SN - 1355-6177
IS - 3
ER -