Neuropsychological abnormalities in patients with dementia in CRF 01_AE HIV-1 infection

V. G. Valcour, P. Sithinamsuwan, S. Nidhinandana, S. Thitivichianlert, S. Ratto-Kim, W. Apateerapong, B. T. Shiramizu, M. S. DeSouza, S. T. Chitpatima, G. Watt, T. Chuenchitra, K. R. Robertson, R. H. Paul, J. C. McArthur, J. H. Kim, C. M. Shikuma

Research output: Contribution to journalArticlepeer-review

Abstract

HIV-associated dementia (HAD) is not firmly established in patients with circulating recombinant form (CRF) 01_AE HIV-1. In this study, we compared neuropsychological performance among 15 Thai individuals with HAD, 15 Thai individuals without HAD, and 30 HIV-negative control subjects. HIV-1 participants were highly active anti-retroviral therapy naive and matched by age, education, and CD4 count. Neuropsychological testing abnormalities were identified in most cognitive domains among HAD vs HIV-negative participants, confirming the presence of HAD in CRF01_AE.

Original languageEnglish (US)
Pages (from-to)525-527
Number of pages3
JournalNeurology
Volume68
Issue number7
DOIs
StatePublished - Feb 2007

ASJC Scopus subject areas

  • Clinical Neurology

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