TY - JOUR
T1 - Neuropsychiatric symptoms in dementia patients with and without a history of traumatic brain injury
AU - Rao, Vani
AU - Rosenberg, Paul
AU - Miles, Quincy Samus
AU - Patadia, Deepa
AU - Treiber, Kate
AU - Bertrand, Melaine
AU - Norton, Maria
AU - Steinberg, Martin
AU - Tschanz, Jo Ann
AU - Lyketsos, Constantine
PY - 2010
Y1 - 2010
N2 - The authors aim to determine if a history of traumatic brain injury (TBI) assessed before dementia onset is associated with a higher risk of neuropsychiatric symptoms after dementia onset. A population-based incident series of people with dementia were assessed for TBI prior to onset of dementia and for neuropsychiatric symptoms after the onset, using the Neuropsychiatric Inventory. Participants with predementia TBI were more likely to exhibit disinhibition (12.7% versus 5.4%, OR=2.8, p=0.02), but not other neuropsychiatric symptoms. Traumatic brain injury may increase the risk of disinhibition in patients with dementia.
AB - The authors aim to determine if a history of traumatic brain injury (TBI) assessed before dementia onset is associated with a higher risk of neuropsychiatric symptoms after dementia onset. A population-based incident series of people with dementia were assessed for TBI prior to onset of dementia and for neuropsychiatric symptoms after the onset, using the Neuropsychiatric Inventory. Participants with predementia TBI were more likely to exhibit disinhibition (12.7% versus 5.4%, OR=2.8, p=0.02), but not other neuropsychiatric symptoms. Traumatic brain injury may increase the risk of disinhibition in patients with dementia.
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U2 - 10.1176/jnp.2010.22.2.166
DO - 10.1176/jnp.2010.22.2.166
M3 - Article
C2 - 20463110
AN - SCOPUS:77952372539
SN - 0895-0172
VL - 22
SP - 166
EP - 172
JO - Journal of Neuropsychiatry and Clinical Neurosciences
JF - Journal of Neuropsychiatry and Clinical Neurosciences
IS - 2
ER -