Neuropsychiatric symptoms in dementia patients with and without a history of traumatic brain injury

Vani Rao, Paul Rosenberg, Quincy Samus Miles, Deepa Patadia, Kate Treiber, Melaine Bertrand, Maria Norton, Martin Steinberg, Jo Ann Tschanz, Constantine Lyketsos

Research output: Contribution to journalArticlepeer-review

Abstract

The authors aim to determine if a history of traumatic brain injury (TBI) assessed before dementia onset is associated with a higher risk of neuropsychiatric symptoms after dementia onset. A population-based incident series of people with dementia were assessed for TBI prior to onset of dementia and for neuropsychiatric symptoms after the onset, using the Neuropsychiatric Inventory. Participants with predementia TBI were more likely to exhibit disinhibition (12.7% versus 5.4%, OR=2.8, p=0.02), but not other neuropsychiatric symptoms. Traumatic brain injury may increase the risk of disinhibition in patients with dementia.

Original languageEnglish (US)
Pages (from-to)166-172
Number of pages7
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume22
Issue number2
DOIs
StatePublished - 2010

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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