Neuroprotective and neurorestorative strategies for parkinson’s disease

Ted M. Dawson; Valina L. Dawson

doi:10.1038/nn941

Neuroprotective and neurorestorative strategies for parkinson’s disease

Ted M. Dawson, Valina L. Dawson

School of Medicine

Research output: Contribution to journal › Review article › peer-review

147 Scopus citations

Abstract

Advances in understanding the molecular mechanisms of cell death and the pathogenesis of sporadic and familial Parkinson’s disease are creating new opportunities for the development of neuroprotective and/or neurorestorative therapies. Here we review many of these advances, highlighting areas and strategies that might be particularly suited to the development of innovative approaches that prevent degeneration and/or restore function in Parkinson’s disease.

Original language	English (US)
Pages (from-to)	1058-1061
Number of pages	4
Journal	Nature neuroscience
Volume	5
Issue number	11s
DOIs	https://doi.org/10.1038/nn941
State	Published - Nov 2002

ASJC Scopus subject areas

General Neuroscience

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title = "Neuroprotective and neurorestorative strategies for parkinson{\textquoteright}s disease",

abstract = "Advances in understanding the molecular mechanisms of cell death and the pathogenesis of sporadic and familial Parkinson{\textquoteright}s disease are creating new opportunities for the development of neuroprotective and/or neurorestorative therapies. Here we review many of these advances, highlighting areas and strategies that might be particularly suited to the development of innovative approaches that prevent degeneration and/or restore function in Parkinson{\textquoteright}s disease.",

author = "Dawson, {Ted M.} and Dawson, {Valina L.}",

note = "Funding Information: We acknowledge the secretarial assistance of Weza Cotman. This work was supported by the National Institutes of Health, the Department of Defense and the Edward and Anna D. Mitchell Family Foundation. We apologize to our colleagues whose work was not discussed in detail or referenced due to space limitations.",

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AU - Dawson, Ted M.

AU - Dawson, Valina L.

N1 - Funding Information: We acknowledge the secretarial assistance of Weza Cotman. This work was supported by the National Institutes of Health, the Department of Defense and the Edward and Anna D. Mitchell Family Foundation. We apologize to our colleagues whose work was not discussed in detail or referenced due to space limitations.

PY - 2002/11

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N2 - Advances in understanding the molecular mechanisms of cell death and the pathogenesis of sporadic and familial Parkinson’s disease are creating new opportunities for the development of neuroprotective and/or neurorestorative therapies. Here we review many of these advances, highlighting areas and strategies that might be particularly suited to the development of innovative approaches that prevent degeneration and/or restore function in Parkinson’s disease.

AB - Advances in understanding the molecular mechanisms of cell death and the pathogenesis of sporadic and familial Parkinson’s disease are creating new opportunities for the development of neuroprotective and/or neurorestorative therapies. Here we review many of these advances, highlighting areas and strategies that might be particularly suited to the development of innovative approaches that prevent degeneration and/or restore function in Parkinson’s disease.

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JO - Nature neuroscience

JF - Nature neuroscience

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Neuroprotective and neurorestorative strategies for parkinson’s disease

Abstract

ASJC Scopus subject areas

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