Neuropeptide modulation of murine erythropoiesis.

R. R. Skelly, J. Fata, S. J. Sharkis, L. Sensenbrenner, A. A. Ansari

Research output: Contribution to journalArticle

Abstract

Neuropeptide modulation of hematopoietic stem cell differentiation was studied in an in vitro murine system. Endorphins were able to influence the erythropoietin-dependent differentiation of bone marrow cells into erythroid colony forming units in a dose dependent manner. The effects on progenitor cell maturation were influenced by the conditions and time of exposure to the endorphins. The modulation of erythropoiesis by the endorphins suggests that these peptides may function as modifiers of the maturation of bone marrow cells.

Original languageEnglish (US)
Pages (from-to)324-330
Number of pages7
JournalAnnals of Clinical and Laboratory Science
Volume17
Issue number5
StatePublished - Sep 1987
Externally publishedYes

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Endorphins
Erythropoiesis
Neuropeptides
Modulation
Bone Marrow Cells
Bone
Cells
Erythroid Precursor Cells
Erythropoietin
Hematopoietic Stem Cells
Stem cells
Cell Differentiation
Stem Cells
Peptides

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Clinical Biochemistry

Cite this

Skelly, R. R., Fata, J., Sharkis, S. J., Sensenbrenner, L., & Ansari, A. A. (1987). Neuropeptide modulation of murine erythropoiesis. Annals of Clinical and Laboratory Science, 17(5), 324-330.

Neuropeptide modulation of murine erythropoiesis. / Skelly, R. R.; Fata, J.; Sharkis, S. J.; Sensenbrenner, L.; Ansari, A. A.

In: Annals of Clinical and Laboratory Science, Vol. 17, No. 5, 09.1987, p. 324-330.

Research output: Contribution to journalArticle

Skelly, RR, Fata, J, Sharkis, SJ, Sensenbrenner, L & Ansari, AA 1987, 'Neuropeptide modulation of murine erythropoiesis.', Annals of Clinical and Laboratory Science, vol. 17, no. 5, pp. 324-330.
Skelly RR, Fata J, Sharkis SJ, Sensenbrenner L, Ansari AA. Neuropeptide modulation of murine erythropoiesis. Annals of Clinical and Laboratory Science. 1987 Sep;17(5):324-330.
Skelly, R. R. ; Fata, J. ; Sharkis, S. J. ; Sensenbrenner, L. ; Ansari, A. A. / Neuropeptide modulation of murine erythropoiesis. In: Annals of Clinical and Laboratory Science. 1987 ; Vol. 17, No. 5. pp. 324-330.
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