Neuropathology of tissues from patients treated by the Brain Tumor Study Group

M. S. Mahaley, F. S. Vogel, P. Burger, N. R. Ghatak

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The histopathologic diagnoses in 718 brain tumor patients entered in the Brain Tumor Study Group were reviewed, as well as those for 53 of these patients who were autopsied later. This review documented instances of progression of histologic anaplasia. Of particular interest in the autopsied cases were several instances of extensive necrosis in white matter distant from persisting glioma following chemotherapy and radiotherapy. This observation suggested the presence of a structural and/or metabolic alteration in the diseased hemisphere that perhaps makes it more susceptible to further alterations secondary to the adjunctive therapy.

Original languageEnglish (US)
Title of host publicationNational Cancer Institute Monograph
Pages77-82
Number of pages6
VolumeNo. 46
StatePublished - 1977
Externally publishedYes

Fingerprint

Brain Neoplasms
Anaplasia
Glioma
Necrosis
Radiotherapy
Drug Therapy
Neuropathology
Therapeutics
White Matter

ASJC Scopus subject areas

  • Cancer Research
  • Medicine(all)

Cite this

Mahaley, M. S., Vogel, F. S., Burger, P., & Ghatak, N. R. (1977). Neuropathology of tissues from patients treated by the Brain Tumor Study Group. In National Cancer Institute Monograph (Vol. No. 46, pp. 77-82)

Neuropathology of tissues from patients treated by the Brain Tumor Study Group. / Mahaley, M. S.; Vogel, F. S.; Burger, P.; Ghatak, N. R.

National Cancer Institute Monograph. Vol. No. 46 1977. p. 77-82.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mahaley, MS, Vogel, FS, Burger, P & Ghatak, NR 1977, Neuropathology of tissues from patients treated by the Brain Tumor Study Group. in National Cancer Institute Monograph. vol. No. 46, pp. 77-82.
Mahaley MS, Vogel FS, Burger P, Ghatak NR. Neuropathology of tissues from patients treated by the Brain Tumor Study Group. In National Cancer Institute Monograph. Vol. No. 46. 1977. p. 77-82
Mahaley, M. S. ; Vogel, F. S. ; Burger, P. ; Ghatak, N. R. / Neuropathology of tissues from patients treated by the Brain Tumor Study Group. National Cancer Institute Monograph. Vol. No. 46 1977. pp. 77-82
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