Abstract
A juvenile Siamese cat with severe, progressive motor disability was shown to have extensive neuronal degeneration caused by accumulation of GM1 ganglioside. Tissues from brain and kidney were markedly deficient in β-galactosidase activity. The disease in this cat is thought to be inherited as an autosomal recessive trait, and is strikingly similar to juvenile GM1 gangliosidosis of children.
Original language | English (US) |
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Pages (from-to) | 838-839 |
Number of pages | 2 |
Journal | Science |
Volume | 174 |
Issue number | 4011 |
DOIs | |
State | Published - 1971 |
ASJC Scopus subject areas
- General