Neuronal and glial cytoskeletons

Don W. Cleveland, Paul N. Hoffman

Research output: Contribution to journalArticle

Abstract

Long-awaited evidence for in vivo functions of the major neuronal microtubule associated proteins indicates that they are directly involved in neurite extension. Companion evidence reveals an intrinsic role for glial intermediate filaments in glial cell extension along neurites and for neurofilaments in establishing axonal caliber. New fluorescence and photoactivation experiments require a re-thinking of models of slow axonal transport and of the part the cytoskeleton plays in axonal guidance.

Original languageEnglish (US)
Pages (from-to)346-353
Number of pages8
JournalCurrent Opinion in Neurobiology
Volume1
Issue number3
DOIs
StatePublished - 1991

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Intermediate Filaments
Neurites
Cytoskeleton
Neuroglia
Axonal Transport
Microtubule-Associated Proteins
Fluorescence

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Neuronal and glial cytoskeletons. / Cleveland, Don W.; Hoffman, Paul N.

In: Current Opinion in Neurobiology, Vol. 1, No. 3, 1991, p. 346-353.

Research output: Contribution to journalArticle

Cleveland, Don W. ; Hoffman, Paul N. / Neuronal and glial cytoskeletons. In: Current Opinion in Neurobiology. 1991 ; Vol. 1, No. 3. pp. 346-353.
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