Abstract
The number of acetylcholine receptors was determined in the neuro-muscular junctions of eight patients with typical myasthenia gravis and in five controls, by means of 125I-labeled α-bungarotoxin binding. The junctional acetylcholine receptors were reduced in the myasthenic muscles as compared with the controls. This reduction in receptors may account for the defect in neuromuscular transmission in myasthenia gravis.
Original language | English (US) |
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Pages (from-to) | 293-295 |
Number of pages | 3 |
Journal | Science |
Volume | 182 |
Issue number | 4109 |
DOIs | |
State | Published - 1973 |
ASJC Scopus subject areas
- General