Neurology of cardiopulmonary resuscitation

Research output: Contribution to journalReview articlepeer-review

Abstract

This chapter aims to provide an up-to-date review of the science and clinical practice pertaining to neurologic injury after successful cardiopulmonary resuscitation. The past two decades have seen a major shift in the science and practice of cardiopulmonary resuscitation, with a major emphasis on postresuscitation neurologic care. This chapter provides a nuanced and thoughtful historic and bench-to-bedside overview of the neurologic aspects of cardiopulmonary resuscitation. A particular emphasis is made on the anatomy and pathophysiology of hypoxic-ischemic encephalopathy, up-to-date management of survivors of cardiopulmonary resuscitation, and a careful discussion on neurologic outcome prediction. Guidance to practice evidence-based clinical care when able and thoughtful, pragmatic suggestions for care where evidence is lacking are also provided. This chapter serves as both a useful clinical guide and an updated, thorough, and state-of-the-art reference on the topic for advanced students and experienced practitioners in the field.

Original languageEnglish (US)
Pages (from-to)593-617
Number of pages25
JournalHandbook of Clinical Neurology
Volume141
DOIs
StatePublished - 2017

Keywords

  • cardiac arrest
  • hypoxic-ischemic encephalopathy
  • neurologic prognostication
  • post cardiac arrest syndrome
  • targeted temperature management
  • therapeutic hypothermia

ASJC Scopus subject areas

  • Medicine(all)
  • Neurology
  • Clinical Neurology

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