Neurological considerations: Autism and Parkinson's disease

Eric Hollander, A. Ting Wang, Ashley Braun, Laura Marsh

Research output: Contribution to journalArticle

Abstract

Within the spectrum of disorders that manifest obsessive-compulsive (OC) features lies a sub-cluster of neurological conditions. Autism and Parkinson's disease (PD) are examples of two such neurological disorders that seem quite dissimilar on the surface. Yet, both conditions can include repetitive behaviors of a compulsive-impulsive nature. Furthermore, while autism and PD differ in other associated symptom domains that shape the course of each disorder, both disorders share some phenomenology in the core domain of repetitive behaviors and involve basal ganglia and frontal lobe dysfunction, similar to OC disorder (OCD). Accordingly, examination of the similarities and differences between autism and PD may provide insight into the pathophysiology and treatment of OC spectrum disorders. The current review focuses on the phenomenology, comorbidity, course of illness, family history, brain circuitry, and treatment of autism and PD, as they relate to OCD and OC spectrum disturbances.

Original languageEnglish (US)
Pages (from-to)43-51
Number of pages9
JournalPsychiatry Research
Volume170
Issue number1
DOIs
StatePublished - Nov 30 2009

Fingerprint

Obsessive-Compulsive Disorder
Autistic Disorder
Parkinson Disease
Compulsive Behavior
Frontal Lobe
Basal Ganglia
Nervous System Diseases
Comorbidity
Brain

Keywords

  • Autism
  • Impulse Control Disorders
  • Obsessive-compulsive disorder
  • Obsessive-compulsive spectrum
  • Parkinson's disease

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Neurological considerations : Autism and Parkinson's disease. / Hollander, Eric; Wang, A. Ting; Braun, Ashley; Marsh, Laura.

In: Psychiatry Research, Vol. 170, No. 1, 30.11.2009, p. 43-51.

Research output: Contribution to journalArticle

Hollander, E, Wang, AT, Braun, A & Marsh, L 2009, 'Neurological considerations: Autism and Parkinson's disease', Psychiatry Research, vol. 170, no. 1, pp. 43-51. https://doi.org/10.1016/j.psychres.2008.07.014
Hollander, Eric ; Wang, A. Ting ; Braun, Ashley ; Marsh, Laura. / Neurological considerations : Autism and Parkinson's disease. In: Psychiatry Research. 2009 ; Vol. 170, No. 1. pp. 43-51.
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