Neurologic outcome of pediatric survivors of cardiac arrest

Donald Harry Shaffner, David G. Nichols, Marie Blanche Tchetgen

Research output: Contribution to journalArticle

Abstract

Introduction: There are 17 studies which report neurologic outcome in 150 children who survive until discharge from the hospital after cardiac arrest. The reported neurologic outcome is highly variable, in part because of the small sample size in individual studies. We gathered a large number of pediatric survivors in a single report to determine the factors that predict a neurologic deficit persisting until hospital discharge (permanent deficit). Methods: The records of 86 children, ages 0-19 years, who survived to hospital discharge after cardiac arrest were analyzed using chi square analysis, the Kruskal-Wallis test, and a multiple logistic regression model. Results: Of the 86 patients, 56 (65%) returned to their pre-arrest neurologic status, 6 (7%) had a transient neurologic deficit which resolved in the hospital, and 24 (28%) developed a permanent neurologic deficit. Analysis of factors associated with the cardiac arrest or resuscitation that were predictive of a permanent neurologic deficit revealed: Univariate predictors of permanent deficit Arrest location p=0.047 Interval between arrest and CPR p=0.02 Hospital CPR duration p=0.004 Asystole p=0.01 Glasgow Coma Score at 24 hours p=0.0001 Initial PaO222

Original languageEnglish (US)
JournalCritical Care Medicine
Volume27
Issue number1 SUPPL.
StatePublished - 1999

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Heart Arrest
Nervous System
Survivors
Neurologic Manifestations
Pediatrics
Cardiopulmonary Resuscitation
Logistic Models
Coma
Resuscitation
Sample Size
Statistical Factor Analysis

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Neurologic outcome of pediatric survivors of cardiac arrest. / Shaffner, Donald Harry; Nichols, David G.; Tchetgen, Marie Blanche.

In: Critical Care Medicine, Vol. 27, No. 1 SUPPL., 1999.

Research output: Contribution to journalArticle

Shaffner, DH, Nichols, DG & Tchetgen, MB 1999, 'Neurologic outcome of pediatric survivors of cardiac arrest', Critical Care Medicine, vol. 27, no. 1 SUPPL..
Shaffner, Donald Harry ; Nichols, David G. ; Tchetgen, Marie Blanche. / Neurologic outcome of pediatric survivors of cardiac arrest. In: Critical Care Medicine. 1999 ; Vol. 27, No. 1 SUPPL.
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