Neurologic aspects of eclampsia

Research output: Contribution to journalArticle

Abstract

Eclampsia continues to be a significant cause of maternal and fetal death throughout the world. Neurologists have a specific role to play in the diagnosis and management of patients who have eclampsia, especially those who have recurrent seizures, raised intracranial pressure, and coma (Table 10). Postpartum patients may be admitted to a neurology service when they present to the emergency department with seizures. The cornerstone of treatment has been blood pressure control and magnesium sulfate with its antivasospastic effect. Should this fail, antiepileptic drugs of proved efficacy, such as diazepam and phenytoin, can be used. Recent studies reveal genetic and mitochondrial defects in eclampsia, but further investigation is warranted to determine the complex underlying pathophysiologic interplay and the optimum prophylactic and therapeutic management.

Original languageEnglish (US)
Pages (from-to)841-861
Number of pages21
JournalNeurologic Clinics
Volume22
Issue number4 SPEC. ISS.
DOIs
StatePublished - Nov 2004

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Eclampsia
Nervous System
Seizures
Magnesium Sulfate
Maternal Death
Fetal Death
Intracranial Pressure
Phenytoin
Neurology
Diazepam
Coma
Anticonvulsants
Postpartum Period
Hospital Emergency Service
Cause of Death
Blood Pressure
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Neurologic aspects of eclampsia. / Kaplan, Peter W.

In: Neurologic Clinics, Vol. 22, No. 4 SPEC. ISS., 11.2004, p. 841-861.

Research output: Contribution to journalArticle

Kaplan, Peter W. / Neurologic aspects of eclampsia. In: Neurologic Clinics. 2004 ; Vol. 22, No. 4 SPEC. ISS. pp. 841-861.
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