Neurokinetics: The dynamics of neurobiology in vivo

Albert Gjedde, William R. Bauer, Dean Foster Wong

Research output: Book/ReportBook

Abstract

This book summarizes 20 years of work on the kinetics of blood-brain transfer and metabolism mechanisms in mammalian brain. The substances affiliated with these mechanisms include glucose, amino acids, monocarboxylic acids, and oxygen. These substances are important to energy metabolism and neurotransmission in the mammalian brain at rest and during activation. To understand the processes addressed by these mechanisms, the book examines the kinetics of compartmentation and compartmental analysis, particularly as they relate to transporter, enzyme, and receptor function. Compartments are subsets of substances separated by transporters and receptors in membranes, and enzymes in cells. This book is divided in six major chapters covering compartmental analysis, kinetic analysis of transport and metabolism, blood-brain transfer and metabolism of glucose, amino acids, and oxygen, and amino acid metabolism and interaction of amino acid metabolites with receptors.

Original languageEnglish (US)
PublisherSpringer US
Number of pages343
ISBN (Print)9781441974099, 9781441974082
DOIs
StatePublished - 2011

Fingerprint

Neurobiology
Amino Acids
Brain
Oxygen
Glucose
Enzymes
Synaptic Transmission
Energy Metabolism
Acids
Membranes

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)

Cite this

Neurokinetics : The dynamics of neurobiology in vivo. / Gjedde, Albert; Bauer, William R.; Wong, Dean Foster.

Springer US, 2011. 343 p.

Research output: Book/ReportBook

Gjedde, Albert ; Bauer, William R. ; Wong, Dean Foster. / Neurokinetics : The dynamics of neurobiology in vivo. Springer US, 2011. 343 p.
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