Neuroimaging findings in acute pediatric diabetic ketoacidosis

Alaysia Barrot, Thierry A G M Huisman, Andrea Poretti

Research output: Contribution to journalArticle

Abstract

Diabetic ketoacidosis (DKA) is a state of severe insulin deficiency and a serious complication in children with diabetes mellitus type 1. In a small number of children, DKA is complicated by injury of the central nervous system. These children have a significant mortality and high long-term neurological morbidity. Cerebral edema is the most common neuroimaging finding in children with DKA and may cause brain herniation. Ischemic or hemorrhagic stroke during the acute DKA episode is less common and accounts for approximately 10% of intracerebral complications of DKA. Here we present the neuroimaging findings of two children with DKA and brain injury. Familiarity with the spectrum of neuroimaging findings seen in pediatric DKA is important to allow early detection as well as initiation of therapy and, hence, prevent complications of the central nervous system.

Original languageEnglish (US)
Pages (from-to)317-322
Number of pages6
JournalNeuroradiology Journal
Volume29
Issue number5
DOIs
StatePublished - Oct 1 2016

Keywords

  • brain
  • children
  • Diabetic ketoacidosis
  • MRI
  • stroke

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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