TY - JOUR
T1 - Neurogenic Stunned Myocardium Following Acute Subarachnoid Hemorrhage
AU - Murthy, Santosh B.
AU - Shah, Shreyansh
AU - Rao, Chethan P.Venkatasubba
AU - Bershad, Eric M.
AU - Suarez, Jose I.
N1 - Publisher Copyright:
© SAGE Publications.
PY - 2015/9/19
Y1 - 2015/9/19
N2 - Neurogenic stunned myocardium (NSM) is a triad of transient left ventricular dysfunction, electrocardiogram changes, and elevation in cardiac enzymes, often mimicking a myocardial infarction. It has been described following acute brain injury. The purported mechanism is catecholamine excess resulting in cardiac dysfunction. From the clinical standpoint, the most frequently encountered electrocardiographic changes are QTc prolongation and ST-T changes, with modest elevations in troponin levels. Basal and mid-ventricular segments of the left ventricle are most commonly involved. NSM poses therapeutic challenges when it occurs secondary to aneurysmal subarachnoid hemorrhage, particularly in the setting of coexisting vasospasm. Overall, NSM carries good prognosis if recognized early, with appropriate management of hemodynamic and cardiopulmonary parameters.
AB - Neurogenic stunned myocardium (NSM) is a triad of transient left ventricular dysfunction, electrocardiogram changes, and elevation in cardiac enzymes, often mimicking a myocardial infarction. It has been described following acute brain injury. The purported mechanism is catecholamine excess resulting in cardiac dysfunction. From the clinical standpoint, the most frequently encountered electrocardiographic changes are QTc prolongation and ST-T changes, with modest elevations in troponin levels. Basal and mid-ventricular segments of the left ventricle are most commonly involved. NSM poses therapeutic challenges when it occurs secondary to aneurysmal subarachnoid hemorrhage, particularly in the setting of coexisting vasospasm. Overall, NSM carries good prognosis if recognized early, with appropriate management of hemodynamic and cardiopulmonary parameters.
KW - Takotsubo cardiomyopathy
KW - myocardial stunning
KW - neurogenic stunned myocardium
KW - subarachnoid hemorrhage
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U2 - 10.1177/0885066613511054
DO - 10.1177/0885066613511054
M3 - Review article
C2 - 24212600
AN - SCOPUS:84939519279
SN - 0885-0666
VL - 30
SP - 318
EP - 325
JO - Journal of Intensive Care Medicine
JF - Journal of Intensive Care Medicine
IS - 6
ER -