Abstract
Introduction What is the evidence that abnormal brain development increases risk? Clues to a molecular mechanism of developmental deviation Why do the clinical manifestations of schizophrenia change over time? Relevant biological events in adolescent brain development Candidate maturational processes and psychosis onset Conclusions References
Original language | English (US) |
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Title of host publication | Schizophrenia |
Subtitle of host publication | Third Edition |
Publisher | Wiley-Blackwell |
Pages | 393-412 |
Number of pages | 20 |
ISBN (Print) | 9781405176972 |
DOIs | |
State | Published - Mar 8 2011 |
Externally published | Yes |
Keywords
- Association with maturational deficits and delays in childhood
- Candidate maturational processes and psychosis onset
- Epistatic interactions of genes - in NRG1/ERBB4/AKT1 signaling pathway
- Evidence that abnormal brain development increases risk
- Genes, objective causative factors - not the only factors
- Major mysteries about schizophrenia - barely addressed by existing research data
- Metachromatic leukodystrophy (MLD), rare genetic disorder - of aryl sulfatase deficiency
- Neurodevelopment hypothesis of schizophrenia - alternative to neurotransmitter hypotheses
- Neurodevelopmental origins of schizophrenia
- Three theoretical pillars of neurodevelopmental view of schizophrenia
ASJC Scopus subject areas
- Medicine(all)