Abstract
Introduction What is the evidence that abnormal brain development increases risk? Clues to a molecular mechanism of developmental deviation Why do the clinical manifestations of schizophrenia change over time? Relevant biological events in adolescent brain development Candidate maturational processes and psychosis onset Conclusions References
| Original language | English (US) |
|---|---|
| Title of host publication | Schizophrenia |
| Subtitle of host publication | Third Edition |
| Publisher | Wiley-Blackwell |
| Pages | 393-412 |
| Number of pages | 20 |
| ISBN (Print) | 9781405176972 |
| DOIs | |
| State | Published - Mar 8 2011 |
| Externally published | Yes |
Keywords
- Association with maturational deficits and delays in childhood
- Candidate maturational processes and psychosis onset
- Epistatic interactions of genes - in NRG1/ERBB4/AKT1 signaling pathway
- Evidence that abnormal brain development increases risk
- Genes, objective causative factors - not the only factors
- Major mysteries about schizophrenia - barely addressed by existing research data
- Metachromatic leukodystrophy (MLD), rare genetic disorder - of aryl sulfatase deficiency
- Neurodevelopment hypothesis of schizophrenia - alternative to neurotransmitter hypotheses
- Neurodevelopmental origins of schizophrenia
- Three theoretical pillars of neurodevelopmental view of schizophrenia
ASJC Scopus subject areas
- Medicine(all)
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Cite this
Weinberger, D. R., & Levitt, P. (2011). Neurodevelopmental Origins of Schizophrenia. In Schizophrenia: Third Edition (pp. 393-412). Wiley-Blackwell. https://doi.org/10.1002/9781444327298.ch19