Neurocognitive correlates of the course of bipolar disorder

Monika Budde, Thomas G. Schulze

Research output: Contribution to journalArticlepeer-review


Significant cognitive dysfunction has been recognized as an important state and trait feature of bipolar disorder. In this article, longitudinal studies comparing cognitive performance in bipolar disorder patients and healthy controls are reviewed. In contrast to cross-sectional reports, current longitudinal research findings do not support a progressive cognitive decline over time. However, a higher within-person instability in cognitive performance was found relative to controls. The need for larger samples remains, as well as for longer and more frequent observations.

Original languageEnglish (US)
Pages (from-to)342-347
Number of pages6
JournalHarvard Review of Psychiatry
Issue number6
StatePublished - Nov 1 2014
Externally publishedYes


  • Attention
  • Bipolar disorder
  • Cognition
  • Executive function
  • Longitudinal
  • Memory
  • Processing speed

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Medicine(all)


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