Neuroblastoma of the Lumbar Spine

Bethany Hung, Zach Pennington, Daniel M. Sciubba

Research output: Contribution to journalArticlepeer-review


Neuroblastoma is a primitive small-round-blue-cell tumor predominately found in pediatric patients. Few cases of neuroblastoma involving the adult spine have been reported. Herein we present the case of a healthy 34-year-old man treated for a large neuroblastoma involving the L3-5 vertebral bodies and prevertebral great vessels. Neoadjuvant chemotherapy led to significant cytoreduction, enabling en bloc resection of the initially unresectable tumor. Adjuvant differentiating therapy was employed, and curative radiation therapy was used to address the first instance of locoregional recurrence. The patient remains alive with stable disease more than 2 years after his initial diagnosis.

Original languageEnglish (US)
Pages (from-to)2-4
Number of pages3
JournalWorld neurosurgery
StatePublished - Jul 2021


  • En bloc resection
  • Lumbar spine
  • Neuroblastic tumor
  • Neuroblastoma
  • Primitive neuroectodermal neoplasm

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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