Neurobiology of Unilateral Spatial Neglect

Research output: Contribution to journalReview articlepeer-review


Hemispatial neglect is a common and disabling consequence of stroke. Earlier studies aimed to identify a single area of the brain where damage caused neglect and sought a single disrupted process that could account for the symptoms. Recent studies have shifted toward identifying component processes and representations underlying spatial attention required for various tasks and identifying areas of the brain responsible for each component that together constitute the network of regions responsible for neglect. This review focuses on recent insights into the mechanisms of neglect, regions of neural dysfunction that cause disruption of particular components or forms of neglect, and potential means of ameliorating neglect. Converging evidence supporting these insights comes from new imaging modalities in acute stroke, functional imaging, transcranial magnetic stimulation, electrophysiological studies in humans, and single-cell recording studies in nonhuman primates.

Original languageEnglish (US)
Pages (from-to)153-163
Number of pages11
JournalThe Neuroscientist
Issue number2
StatePublished - Apr 2006


  • Hemispatial neglect
  • Parietal lobe
  • Rehabilitation
  • Spatial attention
  • Stroke recovery

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


Dive into the research topics of 'Neurobiology of Unilateral Spatial Neglect'. Together they form a unique fingerprint.

Cite this