Neurobiology of Tourette syndrome

Research output: Contribution to journalArticlepeer-review

101 Scopus citations


This article includes a discussion of approaches designed to determine neuroanatomic localization through the use of physical examination, electrophysiologic and neuroradiographic studies, and neuropathologic evaluations. The author reviews the anatomy, function, and biochemistry of frontal-subcortical circuits. Inferred and direct evidence that supports a disorder of frontal-subcortical circuits in Tourette syndrome is presented. Studies investigating specific neurotransmitters are reviewed.

Original languageEnglish (US)
Pages (from-to)357-379
Number of pages23
JournalNeurologic clinics
Issue number2
StatePublished - 1997

ASJC Scopus subject areas

  • Clinical Neurology


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