Abstract
Purpose: To describe a case of panuveitis with occlusive vasculitis leading to the diagnosis of neuro-Behcet disease (NBD) and discuss the relationship between uveitis and NBD. Methods: Case report with a literature review of ocular inflammation in NBD. Results: A 26-year-old woman with a seven-month history of recurrent cerebral venous sinus thromboses (CVST) and right-sided hemiparalysis secondary to rhombencephalitis presented with bilateral panuveitis and occlusive retinal vasculitis. Systemic evaluations were negative for hypercoagulability and infection. Although HLA-51 negative, the diagnosis was consistent with NBD. Conclusion: NBD is a rare subset of BD with a limited number of studies and patients. However, uveitis is more common in adults with parenchymal disease; may predate the development of neurological symptoms. The most common locations of ocular inflammation were posterior and panuveitis. MRI/V of the brain can identify enhancing lesions in the rhombencephalon or CVST in patients with uveitis with neurological findings.
Original language | English (US) |
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Pages (from-to) | 95-103 |
Number of pages | 9 |
Journal | Ocular Immunology and Inflammation |
Volume | 30 |
Issue number | 1 |
DOIs | |
State | Published - 2022 |
Keywords
- Neurobehcet disease
- cerebral venous sinus thrombosis
- occlusive retinal vasculitis
- rhombencephalitis
- uveitis
ASJC Scopus subject areas
- Immunology and Allergy
- Ophthalmology