Neurally mediated hypotension and chronic fatigue syndrome

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66 Scopus citations


A substantial body of clinical evidence now supports an association between various forms of hypotension and both idiopathic chronic fatigue and the chronic fatigue syndrome (CFS). Patients with CFS have a high prevalence of neurally mediated hypotension, and open treatment of this autonomic dysfunction has been associated with improvements in CFS symptoms. Randomized trials are now in progress to evaluate the efficacy of treatments directed at neurally mediated hypotension in those with CFS patients, and the results of these trials should help guide more basic inquiries into the mechanisms of orthostatic intolerance in affected individuals.

Original languageEnglish (US)
Pages (from-to)15S-21S
JournalAmerican Journal of Medicine
Issue number3 A
StatePublished - Sep 28 1998

ASJC Scopus subject areas

  • Medicine(all)


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