Neural prosthesis for motor function restoration in upper limb extremity

Sudip Nag, Kian Ann Ng, Rangarajan Jagadeesan, Swathi Sheshadri, Ignacio Delgado-Martinez, Silvia Bossi, Shih Cheng Yen, Nitish V Thakor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Restoration of motor function in cases of peripheral nerve injury is a challenging problem. Although peripheral nerves do regenerate, the time required for peripheral nerves to regenerate often causes atrophy to occur in the muscles before they can be re-innervated. This paper presents a solution through proximal recording of nerve signals and distal muscle stimulation. A fully implantable hardware architecture is described that can be operated by means of inductive power and MICS band data transmission schemes. Preliminary experiments and validation studies are reported with non-human primates based on recordings in the median nerve, stimulation of hand muscles, and task decoding and classification. This approach shows promise in creating a neural prosthesis capable of restoring hand movements in patients with upper limb peripheral nerve injuries.

Original languageEnglish (US)
Title of host publicationIEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages388-391
Number of pages4
ISBN (Print)9781479923465
DOIs
StatePublished - Dec 9 2014
Event10th IEEE Biomedical Circuits and Systems Conference, BioCAS 2014 - Lausanne, Switzerland
Duration: Oct 22 2014Oct 24 2014

Other

Other10th IEEE Biomedical Circuits and Systems Conference, BioCAS 2014
CountrySwitzerland
CityLausanne
Period10/22/1410/24/14

Fingerprint

Neural prostheses
Restoration
Muscle
Data communication systems
Decoding
Hardware
Experiments

ASJC Scopus subject areas

  • Hardware and Architecture
  • Biomedical Engineering

Cite this

Nag, S., Ng, K. A., Jagadeesan, R., Sheshadri, S., Delgado-Martinez, I., Bossi, S., ... Thakor, N. V. (2014). Neural prosthesis for motor function restoration in upper limb extremity. In IEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings (pp. 388-391). [6981744] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BioCAS.2014.6981744

Neural prosthesis for motor function restoration in upper limb extremity. / Nag, Sudip; Ng, Kian Ann; Jagadeesan, Rangarajan; Sheshadri, Swathi; Delgado-Martinez, Ignacio; Bossi, Silvia; Yen, Shih Cheng; Thakor, Nitish V.

IEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2014. p. 388-391 6981744.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nag, S, Ng, KA, Jagadeesan, R, Sheshadri, S, Delgado-Martinez, I, Bossi, S, Yen, SC & Thakor, NV 2014, Neural prosthesis for motor function restoration in upper limb extremity. in IEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings., 6981744, Institute of Electrical and Electronics Engineers Inc., pp. 388-391, 10th IEEE Biomedical Circuits and Systems Conference, BioCAS 2014, Lausanne, Switzerland, 10/22/14. https://doi.org/10.1109/BioCAS.2014.6981744
Nag S, Ng KA, Jagadeesan R, Sheshadri S, Delgado-Martinez I, Bossi S et al. Neural prosthesis for motor function restoration in upper limb extremity. In IEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2014. p. 388-391. 6981744 https://doi.org/10.1109/BioCAS.2014.6981744
Nag, Sudip ; Ng, Kian Ann ; Jagadeesan, Rangarajan ; Sheshadri, Swathi ; Delgado-Martinez, Ignacio ; Bossi, Silvia ; Yen, Shih Cheng ; Thakor, Nitish V. / Neural prosthesis for motor function restoration in upper limb extremity. IEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 388-391
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