Neural prosthesis for motor function restoration in upper limb extremity

Sudip Nag, Kian Ann Ng, Rangarajan Jagadeesan, Swathi Sheshadri, Ignacio Delgado-Martinez, Silvia Bossi, Shih Cheng Yen, Nitish V. Thakor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Restoration of motor function in cases of peripheral nerve injury is a challenging problem. Although peripheral nerves do regenerate, the time required for peripheral nerves to regenerate often causes atrophy to occur in the muscles before they can be re-innervated. This paper presents a solution through proximal recording of nerve signals and distal muscle stimulation. A fully implantable hardware architecture is described that can be operated by means of inductive power and MICS band data transmission schemes. Preliminary experiments and validation studies are reported with non-human primates based on recordings in the median nerve, stimulation of hand muscles, and task decoding and classification. This approach shows promise in creating a neural prosthesis capable of restoring hand movements in patients with upper limb peripheral nerve injuries.

Original languageEnglish (US)
Title of host publicationIEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages388-391
Number of pages4
ISBN (Electronic)9781479923465
DOIs
StatePublished - Dec 9 2014
Event10th IEEE Biomedical Circuits and Systems Conference, BioCAS 2014 - Lausanne, Switzerland
Duration: Oct 22 2014Oct 24 2014

Publication series

NameIEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings

Other

Other10th IEEE Biomedical Circuits and Systems Conference, BioCAS 2014
CountrySwitzerland
CityLausanne
Period10/22/1410/24/14

    Fingerprint

ASJC Scopus subject areas

  • Hardware and Architecture
  • Biomedical Engineering

Cite this

Nag, S., Ng, K. A., Jagadeesan, R., Sheshadri, S., Delgado-Martinez, I., Bossi, S., Yen, S. C., & Thakor, N. V. (2014). Neural prosthesis for motor function restoration in upper limb extremity. In IEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings (pp. 388-391). [6981744] (IEEE 2014 Biomedical Circuits and Systems Conference, BioCAS 2014 - Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BioCAS.2014.6981744