Network Analysis of a Pkd1-Mouse Model of Autosomal Dominant Polycystic Kidney Disease Identifies HNF4α as a Disease Modifier

Agriculture & Biology

• autosomal dominant polycystic kidney disease 100%
• modifiers (genes) 70%
• animal models 49%
• kidneys 40%
• biochemical pathways 35%
• metabolomics 29%
• disease progression 18%
• recombinases 18%
• kidney diseases 18%
• metabolic diseases 17%
• mutants 16%
• meta-analysis 16%
• gene regulatory networks 15%
• transcriptomics 12%
• inactivation 11%
• alleles 9%
• mutation 9%
• metabolites 9%
• gene expression 8%
• mice 8%
• tissues 6%
• animals 5%
• genes 4%

Medicine & Life Sciences

• Autosomal Dominant Polycystic Kidney 74%
• Metabolic Networks and Pathways 57%
• Metabolomics 31%
• Cysts 24%
• Kidney 22%
• Cystic Kidney Diseases 19%
• Cre recombinase 19%
• Late Onset Disorders 19%
• Gene Expression 17%
• Gene Regulatory Networks 15%
• Chronic Kidney Failure 12%
• Disease Progression 11%
• Software 10%
• Meta-Analysis 10%
• Alleles 10%
• Mutation 7%
• Animals 7%

Earth & Environmental Sciences

• network analysis 62%
• cyst 26%
• mutant 23%
• maturation 22%
• gene 17%
• gene expression 13%
• allele 12%
• meta-analysis 12%
• mutation 11%
• tissue 8%
• animal 7%
• software 7%
• analysis 6%