Nephrogenic rests mimicking Wilm's tumor on CT

Naveen Subhas, Pedram Argani, John P. Gearhart, Stanley S. Siegelman

Research output: Contribution to journalArticlepeer-review

Abstract

Nephrogenic rests (NR) are persistent benign remnants of embryonic renal tissue. A small percentage of these may develop into Wilms' tumor (WT). Radiologic imaging is relied upon to differentiate between these entities, with the hallmark of malignant transformation being growth on serial imaging studies. There is, however, considerable overlap in their imaging characteristics. The authors present a case of two biopsy-proven NR in a 2-year-old girl with sporadic aniridia that were indistinguishable from WT on initial radiologic studies. One of the NR grew on serial imaging studies mimicking a WT, but after resection was confirmed to be a benign hyperplastic NR on pathologic examination.

Original languageEnglish (US)
Pages (from-to)152-155
Number of pages4
JournalPediatric radiology
Volume34
Issue number2
DOIs
StatePublished - Feb 1 2004

Keywords

  • CT
  • MR
  • Nephrogenic rests
  • Renal tumor
  • Wilms' tumor

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging

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