Abstract
We used a modified enzyme-linked immunosorbent assay (ELISA) to investigate tetanus immunity in 232 pregnant Peruvian women. One hundred forty-two (61.2%) had protective antitoxin titers (≥0.01 IU/mL). Protective titers correlated positively with the number of toxoid doses reported during the current pregnancy. A majority of women reporting no toxoid doses during the current pregnancy had at least one prenatal health care visit. We evaluated a toxoid skin test in 44 of the subjects, but it correlated poorly with the ELISA. The modified ELISA is a useful in vitro method for studying tetanus immunity in the developing world.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1754-1756 |
| Number of pages | 3 |
| Journal | American Journal of Public Health |
| Volume | 83 |
| Issue number | 12 |
| State | Published - 1993 |
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ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
Cite this
Neonatal tetanus in Peru : Risk assessment with modified enzyme-linked immunosorbent assay and toxoid skin test. / Vernacchio, L.; Madico, G.; Verastegui, M.; Diaz, F.; Collins, T. S.; Gilman, Robert H.
In: American Journal of Public Health, Vol. 83, No. 12, 1993, p. 1754-1756.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neonatal tetanus in Peru
T2 - Risk assessment with modified enzyme-linked immunosorbent assay and toxoid skin test
AU - Vernacchio, L.
AU - Madico, G.
AU - Verastegui, M.
AU - Diaz, F.
AU - Collins, T. S.
AU - Gilman, Robert H
PY - 1993
Y1 - 1993
N2 - We used a modified enzyme-linked immunosorbent assay (ELISA) to investigate tetanus immunity in 232 pregnant Peruvian women. One hundred forty-two (61.2%) had protective antitoxin titers (≥0.01 IU/mL). Protective titers correlated positively with the number of toxoid doses reported during the current pregnancy. A majority of women reporting no toxoid doses during the current pregnancy had at least one prenatal health care visit. We evaluated a toxoid skin test in 44 of the subjects, but it correlated poorly with the ELISA. The modified ELISA is a useful in vitro method for studying tetanus immunity in the developing world.
AB - We used a modified enzyme-linked immunosorbent assay (ELISA) to investigate tetanus immunity in 232 pregnant Peruvian women. One hundred forty-two (61.2%) had protective antitoxin titers (≥0.01 IU/mL). Protective titers correlated positively with the number of toxoid doses reported during the current pregnancy. A majority of women reporting no toxoid doses during the current pregnancy had at least one prenatal health care visit. We evaluated a toxoid skin test in 44 of the subjects, but it correlated poorly with the ELISA. The modified ELISA is a useful in vitro method for studying tetanus immunity in the developing world.
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UR - http://www.scopus.com/inward/citedby.url?scp=0027132108&partnerID=8YFLogxK
M3 - Article
C2 - 8259811
AN - SCOPUS:0027132108
VL - 83
SP - 1754
EP - 1756
JO - American Journal of Public Health
JF - American Journal of Public Health
SN - 0090-0036
IS - 12
ER -