Neonatal tetanus in Peru: Risk assessment with modified enzyme-linked immunosorbent assay and toxoid skin test

L. Vernacchio, G. Madico, M. Verastegui, F. Diaz, T. S. Collins, R. H. Gilman

Research output: Contribution to journalArticlepeer-review

Abstract

We used a modified enzyme-linked immunosorbent assay (ELISA) to investigate tetanus immunity in 232 pregnant Peruvian women. One hundred forty-two (61.2%) had protective antitoxin titers (≥0.01 IU/mL). Protective titers correlated positively with the number of toxoid doses reported during the current pregnancy. A majority of women reporting no toxoid doses during the current pregnancy had at least one prenatal health care visit. We evaluated a toxoid skin test in 44 of the subjects, but it correlated poorly with the ELISA. The modified ELISA is a useful in vitro method for studying tetanus immunity in the developing world.

Original languageEnglish (US)
Pages (from-to)1754-1756
Number of pages3
JournalAmerican journal of public health
Volume83
Issue number12
DOIs
StatePublished - 1993

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Fingerprint Dive into the research topics of 'Neonatal tetanus in Peru: Risk assessment with modified enzyme-linked immunosorbent assay and toxoid skin test'. Together they form a unique fingerprint.

Cite this