Neighborhood socioeconomic disadvantage is associated with multimorbidity in a geographically-defined community

Alanna M. Chamberlain, Lila J. Finney Rutten, Patrick M. Wilson, Chun Fan, Cynthia M. Boyd, Debra J. Jacobson, Walter A. Rocca, Jennifer L. St Sauver

Research output: Contribution to journalArticle

Abstract

Background: Persons with low socioeconomic status may be disproportionately at risk for multimorbidity. Methods: Adults aged ≥20 years on 4/1/2015 from 7 counties in Minnesota were identified using the Rochester Epidemiology Project (population-based sample). A composite measure of neighborhood socioeconomic disadvantage, the area deprivation index (ADI), was estimated at the census block group level (n = 251). The prevalence of 21 chronic conditions was obtained to calculate the proportion of persons with multimorbidity (≥2 chronic conditions) and severe multimorbidity (≥5 chronic conditions). Hierarchical logistic regression was used to estimate the association of ADI with multimorbidity and severe multimorbidity using odds ratios (OR). Results: Among 198,941 persons (46.7% male, 30.6% aged ≥60 years), the age- and sex-standardized (to the United States 2010 census) median prevalence (Q1, Q3) was 23.4% (21.3%, 25.9%) for multimorbidity and 4.8% (4.0%, 5.7%) for severe multimorbidity. Compared with persons in the lowest quintile of ADI, persons in the highest quintile had a 50% increased risk of multimorbidity (OR 1.50, 95% CI 1.39-1.62) and a 67% increased risk of severe multimorbidity (OR 1.67, 95% CI 1.51-1.86) after adjusting for age, sex, race, and ethnicity. Associations were stronger after further adjustment for individual level of education; persons in the highest quintile had a 78% increased risk of multimorbidity (OR 1.78, 95% CI 1.62-1.96) and a 92% increased risk of severe multimorbidity (OR 1.92, 95% CI 1.72-2.13). There was evidence of interactions between ADI and age, between ADI and sex, and between ADI and education. After age 70 years, no difference in the risk of multimorbidity was observed across quintiles of ADI. The pattern of increasing multimorbidity with increasing ADI was more pronounced in women. Finally, there was less variability across quintiles of ADI for the most highly educated group. Conclusions: Higher ADI was associated with increased risk of multimorbidity, and the associations were strengthened after adjustment for individual level of education, suggesting that neighborhood context plays a role in health above and beyond individual measures of socioeconomic status. Furthermore, associations were more pronounced in younger persons and women, highlighting the importance of interventions to prevent chronic conditions in younger women, in particular.

Original languageEnglish (US)
Article number13
JournalBMC public health
Volume20
Issue number1
DOIs
StatePublished - Jan 6 2020

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Comorbidity
Odds Ratio
Censuses
Education
Social Class
Epidemiology
Logistic Models

Keywords

  • Area deprivation index
  • Geocoding
  • Multimorbidity
  • Socioeconomic status
  • US Census

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Chamberlain, A. M., Finney Rutten, L. J., Wilson, P. M., Fan, C., Boyd, C. M., Jacobson, D. J., ... St Sauver, J. L. (2020). Neighborhood socioeconomic disadvantage is associated with multimorbidity in a geographically-defined community. BMC public health, 20(1), [13]. https://doi.org/10.1186/s12889-019-8123-0

Neighborhood socioeconomic disadvantage is associated with multimorbidity in a geographically-defined community. / Chamberlain, Alanna M.; Finney Rutten, Lila J.; Wilson, Patrick M.; Fan, Chun; Boyd, Cynthia M.; Jacobson, Debra J.; Rocca, Walter A.; St Sauver, Jennifer L.

In: BMC public health, Vol. 20, No. 1, 13, 06.01.2020.

Research output: Contribution to journalArticle

Chamberlain, AM, Finney Rutten, LJ, Wilson, PM, Fan, C, Boyd, CM, Jacobson, DJ, Rocca, WA & St Sauver, JL 2020, 'Neighborhood socioeconomic disadvantage is associated with multimorbidity in a geographically-defined community', BMC public health, vol. 20, no. 1, 13. https://doi.org/10.1186/s12889-019-8123-0
Chamberlain, Alanna M. ; Finney Rutten, Lila J. ; Wilson, Patrick M. ; Fan, Chun ; Boyd, Cynthia M. ; Jacobson, Debra J. ; Rocca, Walter A. ; St Sauver, Jennifer L. / Neighborhood socioeconomic disadvantage is associated with multimorbidity in a geographically-defined community. In: BMC public health. 2020 ; Vol. 20, No. 1.
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abstract = "Background: Persons with low socioeconomic status may be disproportionately at risk for multimorbidity. Methods: Adults aged ≥20 years on 4/1/2015 from 7 counties in Minnesota were identified using the Rochester Epidemiology Project (population-based sample). A composite measure of neighborhood socioeconomic disadvantage, the area deprivation index (ADI), was estimated at the census block group level (n = 251). The prevalence of 21 chronic conditions was obtained to calculate the proportion of persons with multimorbidity (≥2 chronic conditions) and severe multimorbidity (≥5 chronic conditions). Hierarchical logistic regression was used to estimate the association of ADI with multimorbidity and severe multimorbidity using odds ratios (OR). Results: Among 198,941 persons (46.7{\%} male, 30.6{\%} aged ≥60 years), the age- and sex-standardized (to the United States 2010 census) median prevalence (Q1, Q3) was 23.4{\%} (21.3{\%}, 25.9{\%}) for multimorbidity and 4.8{\%} (4.0{\%}, 5.7{\%}) for severe multimorbidity. Compared with persons in the lowest quintile of ADI, persons in the highest quintile had a 50{\%} increased risk of multimorbidity (OR 1.50, 95{\%} CI 1.39-1.62) and a 67{\%} increased risk of severe multimorbidity (OR 1.67, 95{\%} CI 1.51-1.86) after adjusting for age, sex, race, and ethnicity. Associations were stronger after further adjustment for individual level of education; persons in the highest quintile had a 78{\%} increased risk of multimorbidity (OR 1.78, 95{\%} CI 1.62-1.96) and a 92{\%} increased risk of severe multimorbidity (OR 1.92, 95{\%} CI 1.72-2.13). There was evidence of interactions between ADI and age, between ADI and sex, and between ADI and education. After age 70 years, no difference in the risk of multimorbidity was observed across quintiles of ADI. The pattern of increasing multimorbidity with increasing ADI was more pronounced in women. Finally, there was less variability across quintiles of ADI for the most highly educated group. Conclusions: Higher ADI was associated with increased risk of multimorbidity, and the associations were strengthened after adjustment for individual level of education, suggesting that neighborhood context plays a role in health above and beyond individual measures of socioeconomic status. Furthermore, associations were more pronounced in younger persons and women, highlighting the importance of interventions to prevent chronic conditions in younger women, in particular.",
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AU - Chamberlain, Alanna M.

AU - Finney Rutten, Lila J.

AU - Wilson, Patrick M.

AU - Fan, Chun

AU - Boyd, Cynthia M.

AU - Jacobson, Debra J.

AU - Rocca, Walter A.

AU - St Sauver, Jennifer L.

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N2 - Background: Persons with low socioeconomic status may be disproportionately at risk for multimorbidity. Methods: Adults aged ≥20 years on 4/1/2015 from 7 counties in Minnesota were identified using the Rochester Epidemiology Project (population-based sample). A composite measure of neighborhood socioeconomic disadvantage, the area deprivation index (ADI), was estimated at the census block group level (n = 251). The prevalence of 21 chronic conditions was obtained to calculate the proportion of persons with multimorbidity (≥2 chronic conditions) and severe multimorbidity (≥5 chronic conditions). Hierarchical logistic regression was used to estimate the association of ADI with multimorbidity and severe multimorbidity using odds ratios (OR). Results: Among 198,941 persons (46.7% male, 30.6% aged ≥60 years), the age- and sex-standardized (to the United States 2010 census) median prevalence (Q1, Q3) was 23.4% (21.3%, 25.9%) for multimorbidity and 4.8% (4.0%, 5.7%) for severe multimorbidity. Compared with persons in the lowest quintile of ADI, persons in the highest quintile had a 50% increased risk of multimorbidity (OR 1.50, 95% CI 1.39-1.62) and a 67% increased risk of severe multimorbidity (OR 1.67, 95% CI 1.51-1.86) after adjusting for age, sex, race, and ethnicity. Associations were stronger after further adjustment for individual level of education; persons in the highest quintile had a 78% increased risk of multimorbidity (OR 1.78, 95% CI 1.62-1.96) and a 92% increased risk of severe multimorbidity (OR 1.92, 95% CI 1.72-2.13). There was evidence of interactions between ADI and age, between ADI and sex, and between ADI and education. After age 70 years, no difference in the risk of multimorbidity was observed across quintiles of ADI. The pattern of increasing multimorbidity with increasing ADI was more pronounced in women. Finally, there was less variability across quintiles of ADI for the most highly educated group. Conclusions: Higher ADI was associated with increased risk of multimorbidity, and the associations were strengthened after adjustment for individual level of education, suggesting that neighborhood context plays a role in health above and beyond individual measures of socioeconomic status. Furthermore, associations were more pronounced in younger persons and women, highlighting the importance of interventions to prevent chronic conditions in younger women, in particular.

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KW - Geocoding

KW - Multimorbidity

KW - Socioeconomic status

KW - US Census

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