Negative association between asthma and variants of CC16(CC10) on chromosome 11q13 in British and Japanese populations

P. S. Gao, X. Q. Mao, M. Kawai, T. Enomoto, S. Sasaki, O. Tanabe, K. Yoshimura, S. R. Shaldon, Y. Dake, H. Kitano, P. Coull, T. Shirakawa, J. M. Hopkin

Research output: Contribution to journalArticlepeer-review

Abstract

The gene encoding Clara cell-derived inflammatory molecule CC16 has been cited as a candidate gene for atopic asthma on chromosome 11q13. A genetic association study was performed with variants of the CC16 gene on chromosome 11q13 in relation to asthma in British (n = 275) and Japanese (n = 300) populations. No significant association was found between asthma and CC16 genotypes, irrespective of atopic status in these two populations. These data suggest that CC16 might not be the major locus for asthma on 11q13.

Original languageEnglish (US)
Pages (from-to)57-59
Number of pages3
JournalHuman genetics
Volume103
Issue number1
DOIs
StatePublished - Sep 8 1998
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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