Negative association between asthma and variants of CC16(CC10) on chromosome 11q13 in British and Japanese populations

Peisong Gao, X. Q. Mao, M. Kawai, T. Enomoto, S. Sasaki, O. Tanabe, K. Yoshimura, S. R. Shaldon, Y. Dake, H. Kitano, P. Coull, T. Shirakawa, J. M. Hopkin

Research output: Contribution to journalArticle

Abstract

The gene encoding Clara cell-derived inflammatory molecule CC16 has been cited as a candidate gene for atopic asthma on chromosome 11q13. A genetic association study was performed with variants of the CC16 gene on chromosome 11q13 in relation to asthma in British (n = 275) and Japanese (n = 300) populations. No significant association was found between asthma and CC16 genotypes, irrespective of atopic status in these two populations. These data suggest that CC16 might not be the major locus for asthma on 11q13.

Original languageEnglish (US)
Pages (from-to)57-59
Number of pages3
JournalHuman Genetics
Volume103
Issue number1
DOIs
Publication statusPublished - 1998
Externally publishedYes

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ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

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