Needs for an expanded ontology-based classification of adverse drug reactions and related mechanisms

P. E. Zhichkin, B. D. Athey, M. I. Avigan, D. R. Abernethy

Research output: Contribution to journalReview article

Abstract

The growing significance of bioinformatics and systems biology in drug safety research requires a system of adverse-event classification that goes beyond a simple vocabulary. This opinion piece outlines the need for development of an ontology-based framework of describing adverse drug reactions (ADRs) and describes the potential applications for such a framework.

Original languageEnglish (US)
Pages (from-to)963-965
Number of pages3
JournalClinical pharmacology and therapeutics
Volume91
Issue number6
DOIs
StatePublished - Jun 1 2012

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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