Necrotizing enterocolitis in 20 822 infants: Analysis of medical and surgical treatments

Fizan Abdullah, Yiyi Zhang, Melissa Camp, Debraj Mukherjee, Alodia Gabre-Kidan, Paul M. Colombani, David C. Chang

Research output: Contribution to journalArticle

Abstract

Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency of the neonate. Previous information about this disease has largely been gathered from limited series. We analyzed 13 years of the National Inpatient Sample (NIS) and 3 years of the Kidsg Inpatient Database (KID; 1997, 2000, 2003) to generate the most comprehensive profile of outcomes to date of medically versus surgically treated NEC. We identified 20 822 infants with NEC, of whom 15 419 (74.1%) and 5403 (25.9%) were undergoing medical and surgical management, respectively. Overall, surgical patients had greater length of stay, total hospital charges, and mortality. Among infants dying during admission, there was no significant difference in length of stay or charges between the medical and surgical groups. These findings highlight the need for developing a clinically relevant risk stratification tool to identify NEC patients at high risk for death.

Original languageEnglish (US)
Pages (from-to)166-171
Number of pages6
JournalClinical pediatrics
Volume49
Issue number2
DOIs
StatePublished - Mar 1 2010

Keywords

  • Clinical outcomes
  • Medical versus surgical management
  • Necrotizing enterocolitis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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