MRT der myokardialen spätanreicherung während freier atmung unter einsatz einer prospektiven navigatortechnologie mit echtzeit-schichtnachführung

Purpose: A new magnetic resonance imaging approach for detection of myocardial late enhancement during free-breathing was developed. Methods and Results: For suppression of respiratory motion artifacts, a prospective navigator technology including real-time motion correction and a local navigator restore was implemented. Subject specific inversion times were defined from images with incrementally increased inversion times acquired during a single dynamic scout navigator-gated and real-time motion corrected free-breathing scan. Subsequently, MRimaging of myocardial late enhancement was performed with navigator-gated and real-time motion corrected adjacent short axis and long axis (two, three and four chamber) views. This alternative approach was investigated in 7 patients with history of myocardial infarction 12min after i.v. administration of 0.2 mmol/kg body weight gadolinium-DTPA. Conclusion: With the presented navigator-gated and real-time motion corrected sequence for MR-imaging of myocardial late enhancement data can be completely acquired during free-breathing. Time constraints of a breath-hold technique are abolished and optimized patient specific inversion time is ensured.