Natural course of choroidal neovascular membranes within the foveal avascular zone in senile macular degeneration

Susan B Bressler, Neil M Bressler, Stuart L. Fine, Argye Hillis, Robert P. Murphy, R. Joseph Olk, Arnall Patz

Research output: Contribution to journalArticle

Abstract

We divided 96 eyes (93 patients) with senile macular degeneration and choroidal neovascular membranes into two groups-those with juxtafoveal membranes (1 to 250 μ from the center of the foveal avascular zone) and those with subfoveal membranes (0 μ from the center of the zone). After an average follow-up period of 21 months, one of 38 eyes in the juxtafoveal group (3%) had improved two or more lines on the Snellen chart, three eyes (8%) had remained the same, and 34 eyes (89%) had lost two or more lines on the Snellen chart. Although 35 of the 38 eyes (92%) had had initial visual acuities of 6 30 ( 20 100) or better, 27 eyes (71%) had become legally blind. Of the 58 eyes in the subfoveal group, 18 (31%) had remained the same or improved and 40 (69%) had lost two or more lines on the Snellen chart; 41 (70%) had final visual acuities of 6 60 ( 20 200) or worse. Of the 26 eyes in the subfoveal group that had had initial visual acuities of 6 60 ( 20 100) or better (45%), four (15%) had stayed the same and 22 (85%) had lost two or more lines on the Snellen chart. Fourteen of the 26 eyes (54%) had final visual acuities of 6 60 ( 20 200) or worse. Exudative maculopathy developed in the second eye in 13% of patients who initially had unilateral choroidal neovascularization after 12 months, in 22% after 24 months, and in 29% after 36 months, using life table analysis.

Original languageEnglish (US)
Pages (from-to)157-163
Number of pages7
JournalAmerican Journal of Ophthalmology
Volume93
Issue number2
StatePublished - 1982

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Membranes
Visual Acuity
Macular Degeneration, Age-Related, 2
Choroidal Neovascularization
Life Tables

ASJC Scopus subject areas

  • Ophthalmology

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Natural course of choroidal neovascular membranes within the foveal avascular zone in senile macular degeneration. / Bressler, Susan B; Bressler, Neil M; Fine, Stuart L.; Hillis, Argye; Murphy, Robert P.; Olk, R. Joseph; Patz, Arnall.

In: American Journal of Ophthalmology, Vol. 93, No. 2, 1982, p. 157-163.

Research output: Contribution to journalArticle

Bressler, Susan B ; Bressler, Neil M ; Fine, Stuart L. ; Hillis, Argye ; Murphy, Robert P. ; Olk, R. Joseph ; Patz, Arnall. / Natural course of choroidal neovascular membranes within the foveal avascular zone in senile macular degeneration. In: American Journal of Ophthalmology. 1982 ; Vol. 93, No. 2. pp. 157-163.
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