Natural cholera infection-derived immunity in an endemic setting

Mohammad Ali, Michael Emch, Jin Kyung Park, Mohammad Yunus, John Clemens

Research output: Contribution to journalArticle

Abstract

Background. Live oral cholera vaccines may protect against cholera in a manner similar to natural cholera infections. However, information on which to base these vaccines is limited. Methods. The study was conducted in a cholera-endemic population in Bangladesh. Patients with cholera (index patients) detected between 1991 and 2000 were age-matched to 4 cholera-free controls and then followed up during the subsequent 3 years. Results. El Tor cholera was associated with a 65% (95% confidence interval [CI], 37%-81%; P <.001) lower risk of a subsequent El Tor episode. Reduction of the risk of subsequent El Tor cholera was similar for children

Original languageEnglish (US)
Pages (from-to)912-918
Number of pages7
JournalJournal of Infectious Diseases
Volume204
Issue number6
DOIs
StatePublished - Sep 15 2011

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Cholera
Immunity
Infection
Cholera Vaccines
Bangladesh
Risk Reduction Behavior
Vaccines
Confidence Intervals
Population

ASJC Scopus subject areas

  • Infectious Diseases
  • Immunology and Allergy

Cite this

Natural cholera infection-derived immunity in an endemic setting. / Ali, Mohammad; Emch, Michael; Park, Jin Kyung; Yunus, Mohammad; Clemens, John.

In: Journal of Infectious Diseases, Vol. 204, No. 6, 15.09.2011, p. 912-918.

Research output: Contribution to journalArticle

Ali, Mohammad ; Emch, Michael ; Park, Jin Kyung ; Yunus, Mohammad ; Clemens, John. / Natural cholera infection-derived immunity in an endemic setting. In: Journal of Infectious Diseases. 2011 ; Vol. 204, No. 6. pp. 912-918.
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