National Center for Biomedical Ontology: Advancing biomedicine through structured organization of scientific knowledge

Daniel L. Rubin, Suzanna E. Lewis, Chris J. Mungall, Sima Misra, Monte Westerfield, Michael Ashburner, Ida Sim, Christopher G. Chute, Harold Solbrig, Margaret Anne Storey, Barry Smith, John Day-Richter, Natalya F. Noy, Mark A. Musen

Research output: Contribution to journalReview articlepeer-review

115 Scopus citations

Abstract

The National Center for Biomedical Ontology is a consortium that comprises leading informaticians, biologists, clinicians, and ontologists, funded by the National Institutes of Health (NIH) Roadmap, to develop innovative technology and methods that allow scientists to record, manage, and disseminate biomedical information and knowledge in machine-processable form. The goals of the Center are (1) to help unify the divergent and isolated efforts in ontology development by promoting high quality open-source, standards-based tools to create, manage, and use ontologies, (2) to create new software tools so that scientists can use ontologies to annotate and analyze biomedical data, (3) to provide a national resource for the ongoing evaluation, integration, and evolution of biomedical ontologies and associated tools and theories in the context of driving biomedical projects (DBPs), and (4) to disseminate the tools and resources of the Center and to identify, evaluate, and communicate best practices of ontology development to the biomedical community. Through the research activities within the Center, collaborations with the DBPs, and interactions with the biomedical community, our goal is to help scientists to work more effectively in the e-science paradigm, enhancing experiment design, experiment execution, data analysis, information synthesis, hypothesis generation and testing, and understand human disease.

Original languageEnglish (US)
Pages (from-to)185-198
Number of pages14
JournalOMICS A Journal of Integrative Biology
Volume10
Issue number2
DOIs
StatePublished - 2006
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Genetics

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