National assessment of early biliary complications after liver transplantation: Economic implications

David A. Axelrod, Nino Dzebisashvilli, Krista L. Lentine, Huiling Xiao, Mark Schnitzler, Janet E. Tuttle-Newhall, Dorry Segev

Research output: Contribution to journalArticle

Abstract

Background. Despite improvement in surgical technique and medical management of liver transplant recipients, biliary complications remain a frequent cause of posttransplant morbidity and graft loss. Biliary complications require potentially expensive interventions including radiologic procedures and surgical revisions.

Methods. A national data set linking transplant registry and Medicare claims data for 12,803 liver transplant recipients was developed to capture information on complications, treatments, and associated direct medical costs up to 3 years after transplantation.

Results. Biliary complications were more common in recipients of donation after cardiac death compared to donation after brain death allografts (23% vs. 19% P

Conclusion. This national study of biliary complications demonstrates the significant economic impact of this common perioperative complication and suggests a potential target for quality of care improvements.

Original languageEnglish (US)
Pages (from-to)1226-1235
Number of pages10
JournalTransplantation
Volume98
Issue number11
DOIs
StatePublished - Dec 15 2014

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Liver Transplantation
Economics
Transplants
Brain Death
Quality of Health Care
Liver
Medicare
Quality Improvement
Reoperation
Allografts
Registries
Transplantation
Morbidity
Costs and Cost Analysis
Transplant Recipients
Therapeutics
Datasets

Keywords

  • Biliary complications
  • Cost
  • Donation after cardiac death
  • Economic analysis
  • Graft failure
  • Liver transplantation
  • Outcomes research

ASJC Scopus subject areas

  • Transplantation
  • Medicine(all)

Cite this

Axelrod, D. A., Dzebisashvilli, N., Lentine, K. L., Xiao, H., Schnitzler, M., Tuttle-Newhall, J. E., & Segev, D. (2014). National assessment of early biliary complications after liver transplantation: Economic implications. Transplantation, 98(11), 1226-1235. https://doi.org/10.1097/TP.0000000000000197

National assessment of early biliary complications after liver transplantation : Economic implications. / Axelrod, David A.; Dzebisashvilli, Nino; Lentine, Krista L.; Xiao, Huiling; Schnitzler, Mark; Tuttle-Newhall, Janet E.; Segev, Dorry.

In: Transplantation, Vol. 98, No. 11, 15.12.2014, p. 1226-1235.

Research output: Contribution to journalArticle

Axelrod, DA, Dzebisashvilli, N, Lentine, KL, Xiao, H, Schnitzler, M, Tuttle-Newhall, JE & Segev, D 2014, 'National assessment of early biliary complications after liver transplantation: Economic implications', Transplantation, vol. 98, no. 11, pp. 1226-1235. https://doi.org/10.1097/TP.0000000000000197
Axelrod DA, Dzebisashvilli N, Lentine KL, Xiao H, Schnitzler M, Tuttle-Newhall JE et al. National assessment of early biliary complications after liver transplantation: Economic implications. Transplantation. 2014 Dec 15;98(11):1226-1235. https://doi.org/10.1097/TP.0000000000000197
Axelrod, David A. ; Dzebisashvilli, Nino ; Lentine, Krista L. ; Xiao, Huiling ; Schnitzler, Mark ; Tuttle-Newhall, Janet E. ; Segev, Dorry. / National assessment of early biliary complications after liver transplantation : Economic implications. In: Transplantation. 2014 ; Vol. 98, No. 11. pp. 1226-1235.
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