Nanopore sequencing detects structural variants in cancer

Alexis L. Norris, Rachael E. Workman, Yunfan Fan, James Eshleman, Winston Timp

Research output: Contribution to journalArticle

Abstract

Despite advances in sequencing, structural variants (SVs) remain difficult to reliably detect due to the short read length (

Original languageEnglish (US)
Pages (from-to)246-253
Number of pages8
JournalCancer Biology and Therapy
Volume17
Issue number3
DOIs
StatePublished - Mar 3 2016

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Keywords

  • 3rd generation sequencing
  • cancer diagnostics
  • Deletions
  • DNA sequencing
  • inversions
  • nanopore sequencing
  • next generation sequencing
  • structural variation
  • translocations
  • tumor suppressor gene

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Molecular Medicine
  • Pharmacology

Cite this

Nanopore sequencing detects structural variants in cancer. / Norris, Alexis L.; Workman, Rachael E.; Fan, Yunfan; Eshleman, James; Timp, Winston.

In: Cancer Biology and Therapy, Vol. 17, No. 3, 03.03.2016, p. 246-253.

Research output: Contribution to journalArticle

Norris, Alexis L. ; Workman, Rachael E. ; Fan, Yunfan ; Eshleman, James ; Timp, Winston. / Nanopore sequencing detects structural variants in cancer. In: Cancer Biology and Therapy. 2016 ; Vol. 17, No. 3. pp. 246-253.
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