Myxoid Neoplasms

Muhammad I. Zulfiqar, Umer N. Sheikh, Elizabeth A Montgomery

Research output: Contribution to journalArticle

Abstract

Myxoid tumors of soft tissue constitute a heterogeneous group of neoplasms characterized by the presence of a myxoid stromal matrix, which appears on H&E as an amorphous material and may be confused with edema. Superficial myxoid lesions in general are benign and deep ones are malignant. Grossly, they have a variable gelatinous quality and overlapping histologic features that may present diagnostic difficulties for pathologists. Most are sporadic neoplasms, with only a small percentage arising in patients with hereditary disorders. Discussed are key features of classic myxoid lesions, histologic features, characteristic clinical presentations, immunohistochemical patterns, cytogenetic analysis, and differential diagnosis.

Original languageEnglish (US)
Pages (from-to)843-864
Number of pages22
JournalSurgical Pathology Clinics
Volume4
Issue number3
DOIs
StatePublished - Sep 2011

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Neoplasms
Cytogenetic Analysis
Edema
Differential Diagnosis
Pathologists

Keywords

  • Benign lesions
  • Cutaneous myxoma
  • Intramuscular myxoma
  • Malignant neoplasms
  • Myxoid neoplasms

ASJC Scopus subject areas

  • Surgery
  • Pathology and Forensic Medicine

Cite this

Myxoid Neoplasms. / Zulfiqar, Muhammad I.; Sheikh, Umer N.; Montgomery, Elizabeth A.

In: Surgical Pathology Clinics, Vol. 4, No. 3, 09.2011, p. 843-864.

Research output: Contribution to journalArticle

Zulfiqar, Muhammad I. ; Sheikh, Umer N. ; Montgomery, Elizabeth A. / Myxoid Neoplasms. In: Surgical Pathology Clinics. 2011 ; Vol. 4, No. 3. pp. 843-864.
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