Mycordial stunning is caused by decreased myofilament sensitivity to Ca2+ after ischemia. Ischemia preconditioning is an adoptive response to brief ischemia insults which renders the heart resistant to lethal injury. Both have a clear clinical implications. The former rationalizes the common postoperative requirement for intensive short-term inotropic support in patients who eventually proceed to recovery, while the later may help to limit ischemic damage during cardioplegia and hypothermic circulatory arrest.
|Original language||English (US)|
|Number of pages||9|
|Journal||Problems in Anesthesia|
|State||Published - Jan 1 2001|
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine