Myocardial recovery after hypothermic arrest: a comparison of oxygenated crystalloid to blood cardioplegia. The role of calcium.

R. F. Heitmiller, L. W. DeBoer, G. A. Geffin, K. W. Toal, J. T. Fallon, L. J. Drop, R. S. Teplick, D. D. O'Keefe, W. M. Daggett

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Abstract

We compared multidose crystalloid hyperkalemic cardioplegic solutions with and without added red cells in 24 canine hearts subjected to 5 hr of arrest at 10 degrees C. All cardioplegic solutions were fully oxygenated at 4 degrees C before delivery. Since blood cardioplegia contained Ca++ carried over with the red cells, Ca++ was added to the crystalloid solution in one group. The table below shows the hematocrit (HCT) and ionized Ca++ concentrations of the cardioplegic solutions, and coronary arteriovenous oxygen difference during infusion of cardioplegic solution (AVO2) (ml O2/100 ml). Recovery during reperfusion is shown as percent of prearrest left ventricular function (LVF) and prearrest myocardial ATP concentration.

Original languageEnglish (US)
JournalCirculation
Volume72
Issue number3 Pt 2
Publication statusPublished - Sep 1985
Externally publishedYes

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ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Heitmiller, R. F., DeBoer, L. W., Geffin, G. A., Toal, K. W., Fallon, J. T., Drop, L. J., ... Daggett, W. M. (1985). Myocardial recovery after hypothermic arrest: a comparison of oxygenated crystalloid to blood cardioplegia. The role of calcium. Circulation, 72(3 Pt 2).