Myocardial perfusion SPECT using a rotating multi-segment slant-hole collimator

Research output: Contribution to journalArticle

Abstract

Purpose: A rotating multi-segment slant-hole (RMSSH) collimator is able to provide much higher (∼3 times for four-segment collimator with 30° slant angle) sensitivity than a parallel-hole (PH) collimator with the similar spatial resolution for imaging small organs such as the heart and the breast. In this article, the authors evaluated the performance of myocardial perfusion SPECT (MPS) using a RMSSH collimator compared to MPS using the low-energy high-resolution parallel-hole collimators. Methods: The authors conducted computer simulation studies using the NURBS-based cardiac-torso phantom, receiver operative characteristic (ROC) analysis using the channelized Hotelling observer, physical phantom experiments, and pilot patient studies to evaluate the performance of MPS using a rotating four-segment slant-hole (R4SSH) collimator with respect to MPS using a PH collimator. Results: In the simulation study, the R4SSH MPS provides images with superior contrast-noise trade-off than those of PH MPS with the same acquisition time. The defect detectability in terms of the largest area under the ROC curve for R4SSH MPS is significantly higher than those of PH MPS with p -values

Original languageEnglish (US)
Pages (from-to)1610-1618
Number of pages9
JournalMedical Physics
Volume37
Issue number4
DOIs
StatePublished - 2010

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Single-Photon Emission-Computed Tomography
Perfusion
Torso
Computer Simulation
Noise
Breast

Keywords

  • Myocardial perfusion SPECT
  • Parallel-hole collimator
  • Rotating multisegment slant-hole collimator

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

Myocardial perfusion SPECT using a rotating multi-segment slant-hole collimator. / Liu, Chi; Xu, Jingyan; Tsui, Benjamin.

In: Medical Physics, Vol. 37, No. 4, 2010, p. 1610-1618.

Research output: Contribution to journalArticle

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