TY - JOUR
T1 - Myocardial Infarction as a Clinical End Point in Research
T2 - What Are We Really Talking About?
AU - Defilippis, Andrew P.
AU - Nasir, Khurram
AU - Blaha, Michael J.
N1 - Publisher Copyright:
© 2019 American Heart Association, Inc.
PY - 2019/6/7
Y1 - 2019/6/7
N2 - Reflecting the greater understanding of the many diverse causes of myocardial injury, international consensus definition of myocardial injury now includes nonischemic causes of myocardial injury and several etiologically distinct subtypes of myocardial infarction (MI). It is time that all ongoing prospective cohorts and clinical trials systematically differentiate and report on all the etiologically distinct types of myocardial injury. Such reporting will undoubtedly advance the fundamental understanding of the epidemiology of myocardial injury events, including differing risk factor associations, allowing better prediction, prevention, and pharmacotherapies for all identified subtypes of myocardial injury events-including all subtypes of MI.
AB - Reflecting the greater understanding of the many diverse causes of myocardial injury, international consensus definition of myocardial injury now includes nonischemic causes of myocardial injury and several etiologically distinct subtypes of myocardial infarction (MI). It is time that all ongoing prospective cohorts and clinical trials systematically differentiate and report on all the etiologically distinct types of myocardial injury. Such reporting will undoubtedly advance the fundamental understanding of the epidemiology of myocardial injury events, including differing risk factor associations, allowing better prediction, prevention, and pharmacotherapies for all identified subtypes of myocardial injury events-including all subtypes of MI.
KW - acute coronary syndrome
KW - ischemia
KW - myocardial infarction
KW - prospective studies
KW - risk factors
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U2 - 10.1161/CIRCRESAHA.119.315101
DO - 10.1161/CIRCRESAHA.119.315101
M3 - Review article
C2 - 31170039
AN - SCOPUS:85067500641
SN - 0009-7330
VL - 124
SP - 1701
EP - 1703
JO - Circulation research
JF - Circulation research
IS - 12
ER -