Myocardial Infarction as a Clinical End Point in Research: What Are We Really Talking About?

Andrew P. Defilippis, Khurram Nasir, Michael J. Blaha

Research output: Contribution to journalReview articlepeer-review

Abstract

Reflecting the greater understanding of the many diverse causes of myocardial injury, international consensus definition of myocardial injury now includes nonischemic causes of myocardial injury and several etiologically distinct subtypes of myocardial infarction (MI). It is time that all ongoing prospective cohorts and clinical trials systematically differentiate and report on all the etiologically distinct types of myocardial injury. Such reporting will undoubtedly advance the fundamental understanding of the epidemiology of myocardial injury events, including differing risk factor associations, allowing better prediction, prevention, and pharmacotherapies for all identified subtypes of myocardial injury events-including all subtypes of MI.

Original languageEnglish (US)
Pages (from-to)1701-1703
Number of pages3
JournalCirculation research
Volume124
Issue number12
DOIs
StatePublished - Jun 7 2019

Keywords

  • acute coronary syndrome
  • ischemia
  • myocardial infarction
  • prospective studies
  • risk factors

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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