Myocardial first-pass perfusion cardiovascular magnetic resonance: History, theory, and current state of the art

Bernhard L. Gerber, Subha V. Raman, Krishna Nayak, Frederick H. Epstein, Pedro Ferreira, Leon Axel, Dara L. Kraitchman

Research output: Contribution to journalReview articlepeer-review

Abstract

In less than two decades, first-pass perfusion cardiovascular magnetic resonance (CMR) has undergone a wide range of changes with the development and availability of improved hardware, software, and contrast agents, in concert with a better understanding of the mechanisms of contrast enhancement. The following review provides a perspective of the historical development of first-pass CMR, the developments in pulse sequence design and contrast agents, the relevant animal models used in early preclinical studies, the mechanism of artifacts, the differences between 1.5T and 3T scanning, and the relevant clinical applications and protocols. This comprehensive overview includes a summary of the past clinical performance of first-pass perfusion CMR and current clinical applications using state-of-the-art methodologies.

Original languageEnglish (US)
Article number18
JournalJournal of Cardiovascular Magnetic Resonance
Volume10
Issue number1
DOIs
StatePublished - 2008

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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