Myeloid sarcoma of the hepatobiliary system: A case series and review of the literature

Kelly J. Norsworthy, Bhavana Bhatnagar, Zeba N. Singh, Ivana Gojo

Research output: Contribution to journalArticle

Abstract

Myeloid sarcoma (MS) is a rare extramedullary presentation of myeloid malignancies, most commonly seen in association with acute myeloid leukemia (AML). Although MS can develop in any organ, the involvement of the hepatobiliary system is rare. With clinical manifestations of jaundice, abdominal pain and other gastrointestinal symptoms, MS presenting at this location can be a challenge to diagnose, particularly in patients with no known history of hematologic malignancy. This may cause delay in proper management. Here we report 3 cases from a single institution and a review of the literature concerning the epidemiology, clinical presentation, treatment and outcomes in patients with MS of the liver, biliary tree and pancreas.

Original languageEnglish (US)
Pages (from-to)241-251
Number of pages11
JournalActa Haematologica
Volume135
Issue number4
DOIs
StatePublished - May 1 2016

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Keywords

  • Acute myeloid leukemia
  • Biliary tract
  • Extramedullary sites
  • Liver
  • Myeloid sarcoma
  • Pancreas

ASJC Scopus subject areas

  • Hematology

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