Myelinated nociceptive afferents account for the hyperalgesia that follows a burn to the hand

Research output: Contribution to journalArticle

Abstract

Monkeys and human subjects were exposed to a series of thermal stimuli before and after a 53°C, 30-second burn to the glabrous skin of the hand. The responses of C- and A-fiber nociceptive afferents in the monkeys and subjective responses by the humans were compared. The burn resulted in increased sensitivity of the A fibers, decreased sensitivity of the C fibers, and increased pain sensibility (hyperalgesia) in the human subjects.

Original languageEnglish (US)
Pages (from-to)1529-1531
Number of pages3
JournalScience
Volume213
Issue number4515
StatePublished - 1981

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Hyperalgesia
Myelinated Nerve Fibers
Hand
Haplorhini
Unmyelinated Nerve Fibers
Hot Temperature
Pain
Skin

ASJC Scopus subject areas

  • General

Cite this

Myelinated nociceptive afferents account for the hyperalgesia that follows a burn to the hand. / Meyer, Richard; Campbell, James N.

In: Science, Vol. 213, No. 4515, 1981, p. 1529-1531.

Research output: Contribution to journalArticle

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