Mycosis fungoides: Epidemiologic observations

M. H. Greene, N. A. Dalager, S. I. Lamberg, C. E. Argyropoulos, J. F. Fraumeni

Research output: Contribution to journalArticlepeer-review


An analysis of cases from a multi-hospital, pathologically verified clinical series and of deaths from US mortality statistics available at the county level for 1950-1975 (excluding 1972) was made in order to obtain information on the etiology of mycosis fungoides (MF). Despite the absence of an appropriate comparison group, the cases seemed to have a high frequency of antecedent allergies, fungal and viral skin infections, sun sensitivity, familial aggregation of lymphoma and leukemia, and employment in a manufacturing occupation (especially petrochemical, textile, metal, and machinery industries). The mortality survey revealed a predominance among males, nonwhites, and residents of the northeastern US, the latter due partly to an association between MF mortality and population size. The influence of occupational exposures was suggested by the excessive MF mortality rates in counties where petroleum, rubber, primary and fabricated metal, machinery, and printing industries were located.

Original languageEnglish (US)
Pages (from-to)597-606
Number of pages10
JournalCancer Treatment Reports
Issue number4
StatePublished - Dec 1 1979
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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